Brian D. Biggers : rechercher sur Z-Library

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Livres
Articles (86)
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1

High dose genistein aglycone in Sanfilippo syndrome: Results of a randomised, double-blinded, placebo controlled clinical trial

Ghosh, Arunabha, Rust, Stewart, Weisberg, Daniel, Canal, Maria, Wijburg, Frits A., Vaz, Fred M., Tylee, Karen L., Church, Heather J., Hepburn, Michelle, Bigger, Brian W., Jones, Simon A.

Journal:

Molecular Genetics and Metabolism

Année:

2018

Langue:

english

Fichier:

PDF, 69 KB

english, 2018

2

8 Internalization of isolated mitochondria by mammalian cells

Volkmar Weissig, Eyad Katrangi, Gerard D’Souza, Sarathi V. Boddapati, Mariola Kulawiec, Keshav Singh, Brian Bigger

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 47 KB

english, 2007

3

Neuropathological changes are more pronounced in mouse models of Mucopolysaccharidosis (MPS) type IIIA and IIIB over MPS I

Wilkinson, Fiona, Holley, Rebecca, Langford-Smith, Kia, Badrinath, Soumya, Liao, Aiyin, Langford-Smith, Alex, Cooper, Jonathan, Jones, Simon, Wraith, Ed, Wynn, Rob, Merry, Catherine, Bigger, Brian

Journal:

Molecular Genetics and Metabolism

Année:

2013

Langue:

english

Fichier:

PDF, 81 KB

english, 2013

4

Sleep disordered breathing in mucopolysaccharidosis I: a multivariate analysis of patient, therapeutic and metabolic correlators modifying long term clinical outcome

Pal, Abhijit Ricky, Langereis, Eveline J, Saif, Muhammad A, Mercer, Jean, Church, Heather J, Tylee, Karen L, Wynn, Robert F, Wijburg, Frits A, Jones, Simon A, Bruce, Iain A, Bigger, Brian W

Journal:

Orphanet Journal of Rare Diseases

Année:

2015

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2015

5

Pre-clinical safety and efficacy evaluation of GMP lentiviral vector in preparation for a clinical trial of hematopoietic stem cell gene therapy in MPS IIIA

Ellison, Stuart M., Wood, Shaun, Sergijenko, Ana, Armant, Myriam, Chan, Lucas, Farzaneh, Farzin, Jones, Simon, Wynn, Rob, Gaspar, Bobby, Biffi, Alessandra, Bigger, Brian

Journal:

Molecular Genetics and Metabolism

Année:

2018

Langue:

english

Fichier:

PDF, 56 KB

english, 2018

6

Immune activation or immunomodulation in the brains of MPS IIIB mice? Commentary on “innate and adaptive immune activation in the brain of MPS IIIB mouse model”

Louise D. Archer, Kia Langford, Brian Bigger, James E. Fildes

Journal:

Journal of Neuroscience Research

Année:

2010

Langue:

english

Fichier:

PDF, 35 KB

english, 2010

7

Introduction of Chloramphenicol Resistance into the Modified Mouse Mitochondrial Genome: Cloning of Unstable Sequences by Passage through Yeast

Brian Bigger, Oleg Tolmachov, Jean-Marc Collombet, Charles Coutelle

Journal:

Analytical Biochemistry

Année:

2000

Langue:

english

Fichier:

PDF, 111 KB

english, 2000

8

RecET driven chromosomal gene targeting to generate a RecA deficientEscherichia colistrain for Cre mediated production of minicircle DNA

Oleg Tolmachov, Iwona Palaszewski, Brian Bigger, Charles Coutelle

Journal:

BMC Biotechnology

Année:

2006

Langue:

english

Fichier:

PDF, 869 KB

english, 2006

9

Heparin cofactor II-thrombin complex and dermatan sulphate:chondroitin sulphate ratio are biomarkers of short- and long-term treatment effects in mucopolysaccharide diseases

Kia Jane Langford-Smith, Jean Mercer, June Petty, Karen Tylee, Heather Church, Jane Roberts, Gill Moss, Simon Jones, Rob Wynn, J. Ed Wraith, Brian W. Bigger

Journal:

Journal of Inherited Metabolic Disease

Année:

2011

Langue:

english

Fichier:

PDF, 318 KB

english, 2011

10

Trial and Error: How the Unclonable Human Mitochondrial Genome was Cloned in Yeast

Brian W. Bigger, Ai-Yin Liao, Ana Sergijenko, Charles Coutelle

Journal:

Pharmaceutical Research

Année:

2011

Langue:

english

Fichier:

PDF, 322 KB

english, 2011

11

Tipping the scales in favour of mitochondrial gene therapy

Bigger, Brian, Collombet, Jean-Marc, Coutelle, Charles

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 73 KB

english, 1999

12

Circulating Tumor Cells in Patients Undergoing Surgery for Primary Breast Cancer: Preliminary Results of a Pilot Study

Brian Biggers, Sally Knox, Michael Grant, John Kuhn, John Nemunatitis, Tammy Fisher, Jeff Lamont

Journal:

Annals of Surgical Oncology

Année:

2009

Langue:

english

Fichier:

PDF, 174 KB

english, 2009

13

Inframammary Approach for Removal of Giant Juvenile Fibroadenomas

Brian D. Biggers, Jeff P. Lamont, Chukwuemeka N. Etufugh, Sally K. Knox

Journal:

Journal of the American College of Surgeons

Année:

2009

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2009

14

Improved Metabolic Correction in Patients with Lysosomal Storage Disease Treated with Hematopoietic Stem Cell Transplant Compared with Enzyme Replacement Therapy

Robert F. Wynn, J. Ed Wraith, Jean Mercer, Anne O'Meara, Karen Tylee, Margaret Thornley, Heather J. Church, Brian W. Bigger

Journal:

The Journal of Pediatrics

Année:

2009

Langue:

english

Fichier:

PDF, 326 KB

english, 2009

15

Predictive value of preoperative left ventricular ejection fraction and functional class for mortality and morbidity after high-risk coronary artery bypass grafting

Brian Olshansky, E.Alexander Telfer, Anne B. Curtis, J.Thomas Bigger Jr.

Journal:

The American Journal of Cardiology

Année:

2000

Langue:

english

Fichier:

PDF, 76 KB

english, 2000

16

Murine leukemia following irradiation conditioning for transplantation of lentivirally-modified hematopoietic stem cells

Elena K. Siapati, Brian W. Bigger, Karl Kashofer, Mike Themis, Adrian J. Thrasher, Dominique Bonnet

Journal:

European Journal of Haematology

Année:

2007

Langue:

english

Fichier:

PDF, 756 KB

english, 2007

17

Global natures: from utter failures to the possible

Brian Grabbatin, Patrick Bigger

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 91 KB

english, 2012

18

Circadian rhythm and suprachiasmatic nucleus alterations in the mouse model of mucopolysaccharidosis IIIB

Maria M. Canal, Fiona L. Wilkinson, Jonathan D. Cooper, J. Ed Wraith, Rob Wynn, Brian W. Bigger

Journal:

Behavioural Brain Research

Année:

2010

Langue:

english

Fichier:

PDF, 1.77 MB

english, 2010

19

10. Developing a lentiviral gene delivery system in stem cells for the treatment of Sanfilippo syndrome (MPS IIIA)

Brian Bigger, Bill Bennett, Fiona Wilkinson, Kia Langford, Angharad O’Leary, Ed Wraith, Rob Wynn

Journal:

Molecular Genetics and Metabolism

Année:

2008

Langue:

english

Fichier:

PDF, 43 KB

english, 2008

20

Genistein reduces lysosomal storage in peripheral tissues of mucopolysaccharide IIIB mice

Marcelina Malinowska, Fiona L. Wilkinson, William Bennett, Kia J. Langford-Smith, H. Angharad O’Leary, Joanna Jakobkiewicz-Banecka, Rob Wynn, J. Ed Wraith, Grzegorz Wegrzyn, Brian W. Bigger

Journal:

Molecular Genetics and Metabolism

Année:

2009

Langue:

english

Fichier:

PDF, 737 KB

english, 2009

21

15. The effect of long-term substrate reduction therapy withgenistein in a mouse model of MPS IIIB

Brian Bigger, Marcela Malinowska, Fiona Wilkinson, Kia Langford-Smith, Alexander Langford-Smith, Rob Wynn, Ed Wraith, Grzegorz Wegrzyn, Brian Bigger

Journal:

Molecular Genetics and Metabolism

Année:

2010

Langue:

english

Fichier:

PDF, 41 KB

english, 2010

22

Evaluation of heparin cofactor II–thrombin complex as a biomarker on blood spots from mucopolysaccharidosis I, IIIA and IIIB mice

Kia Langford-Smith, Malani Arasaradnam, J. Ed Wraith, Rob Wynn, Brian W. Bigger

Journal:

Molecular Genetics and Metabolism

Année:

2010

Langue:

english

Fichier:

PDF, 247 KB

english, 2010

23

Lentiviral mediated stem cell gene therapy corrects a mouse model of mucopolysaccharidosis type IIIA

Brian Bigger, Alex Langford-Smith, Fiona Wilkinson, Kia Langford-Smith, Ana Sergijenko, Ed Wraith, Rob Wynn

Journal:

Molecular Genetics and Metabolism

Année:

2011

Langue:

english

Fichier:

PDF, 58 KB

english, 2011

24

Glycan-based biomarkers for the mucopolysaccharidoses

Jillian Brown, Roger Lawrence, Kia Langford-Smith, Steven Le, Charles Glass, Patricia Dickson, Brian Bigger, Jeffrey Esko, Brett Crawford

Journal:

Molecular Genetics and Metabolism

Année:

2011

Langue:

english

Fichier:

PDF, 58 KB

english, 2011

25

Serum HCII-T and urinary DS:CS ratio are both predictive biomarkers of treatment outcome in patients with MPS I, II and VI

Brian Bigger, Kia Langford-Smith, Jean Mercer, June Petty, Karen Tylee, Heather Church, Jane Roberts, Gill Moss, Simon Jones, Rob Wynn, Ed Wraith

Journal:

Molecular Genetics and Metabolism

Année:

2011

Langue:

english

Fichier:

PDF, 71 KB

english, 2011

26

The migratory and mitotic behaviour of glioma stem cells in vitro: Optimisation of live-cell time-lapse microscopy

James Barnett, Omar Pathmanaban, Ian Kamaly-Asl, Brian Bigger

Journal:

International Journal of Surgery

Année:

2011

Langue:

english

Fichier:

PDF, 64 KB

english, 2011

27

The Bone Marrow Functionally Contributes to Liver Fibrosis

Francesco P. Russo, Malcolm R. Alison, Brian W. Bigger, Eunice Amofah, Aikaterini Florou, Farhana Amin, George Bou–Gharios, Rosemary Jeffery, John P. Iredale, Stuart J. Forbes

Journal:

Gastroenterology

Année:

2006

Langue:

english

Fichier:

PDF, 6.40 MB

english, 2006

28

Analytical strategies for characterization of oxysterol lipidomes: Liver X receptor ligands in plasma

Griffiths, William J., Crick, Peter J., Wang, Yuchen, Ogundare, Michael, Tuschl, Karin, Morris, Andrew A., Bigger, Brian W., Clayton, Peter T., Wang, Yuqin

Journal:

Free Radical Biology and Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2013

29

Successful allogeneic bone marrow transplant for Niemann–Pick disease type

Bonney, Denise K., OâMeara, Anne, Shabani, Abdu, Imrie, Jackie, Bigger, Brian W., Jones, Simon, Wraith, James E., Wynn, Robert F.

Journal:

Journal of Inherited Metabolic Disease

Année:

2010

Langue:

english

Fichier:

PDF, 148 KB

english, 2010

30

Mucopolysaccharide diseases: A complex interplay between neuroinflammation, microglial activation and adaptive immunity

Archer, Louise D., Langford-Smith, Kia J., Bigger, Brian W., Fildes, James E.

Journal:

Journal of Inherited Metabolic Disease

Année:

2014

Langue:

english

Fichier:

PDF, 440 KB

english, 2014

31

Mouse model of MPS III type C defines pathophysiology of the disease

Pshezhetsky, Alexey, Martins, Carla, Grigoryeva, Lubov, Dridy, Larbi, Dormoy-Raclet, Virginie, Di Cristo, Graziella, Bigger, Brian, Ausseil, Jerome Ausseil, lková, Helena H. lková H., Hrebícek, Martin

Journal:

Molecular Genetics and Metabolism

Année:

2013

Langue:

english

Fichier:

PDF, 65 KB

english, 2013

32

Biomarker levels in MPS I patients on long term enzyme replacement therapy: correlations with antibody levels and antibody mediated cellular uptake inhibition

Langereis, Eveline, van Vlies, Naomi, Jones, Simon, Schreider, Lena, Wagemans, Tom, Wijburg, Frits, Bigger, Brian

Journal:

Molecular Genetics and Metabolism

Année:

2014

Langue:

english

Fichier:

PDF, 128 KB

english, 2014

33

EPIDEMIC CEREBRO-SPINAL FEVER.

Saif, Muhammad, Jones, Simon, Vellodi, Ashok, Mitchell, John, Clark, Lorne, Mercer, Jean, Tylee, Karen, Church, Heather, Bigger, Brian

Journal:

Année:

1907

Langue:

english

Fichier:

PDF, 180 KB

english, 1907

34

Functionally neutralizing anti-laronidase antibodies and their clinical effects on three patients with Hurler–Scheie syndrome undergoing enzyme replacement therapy

Saif, Muhammad, Jones, Simon, Vellodi, Ashok, Mitchell, John, Clark, Lorne, Mercer, Jean, Tylee, Karen, Church, Heather, Bigger, Brian

Journal:

Molecular Genetics and Metabolism

Année:

2013

Langue:

english

Fichier:

PDF, 66 KB

english, 2013

35

Heparan sulphate inhibits CXCL12-mediated hematopoietic cell migration and engraftment in mucopolysaccharidosis type I mice

Bigger, Brian, Watson, Angharad, Holley, Rebecca, Langford-Smith, Kia, Wilkinson, Fiona, van Kuppevelt, Toin, Wynn, Rob, Wraith, Ed, Merry, Catherine

Journal:

Molecular Genetics and Metabolism

Année:

2013

Langue:

english

Fichier:

PDF, 72 KB

english, 2013

36

The majority of MPS I patients tested raise inhibitory allo-antibodies against enzyme replacement therapy

Saif, Muhammad, Brookes, Karen E., Mercer, Jean, Tylee, Karen L., Church, Heather J., Bonney, Denise K., Jones, Simon, Wraith, J. Ed, Wynn, Robert F., Bigger, Brian W.

Journal:

Molecular Genetics and Metabolism

Année:

2013

Langue:

english

Fichier:

PDF, 66 KB

english, 2013

37

Four-Contact Glove Probe Method for Rapid Recording of Cardiac Electrograms during Surgery

Spotnitz, Henry M., Gliklich, Jerry I., Ross, Samuel, Reiffel, James A., Malm, James R., Bigger Jr., J. Thomas, Hoffman, Brian F.

Journal:

The Annals of Thoracic Surgery

Année:

1982

Langue:

english

Fichier:

PDF, 579 KB

english, 1982

38

Configuring latent Dirichlet allocation based feature location

Biggers, Lauren R., Bocovich, Cecylia, Capshaw, Riley, Eddy, Brian P., Etzkorn, Letha H., Kraft, Nicholas A.

Journal:

Empirical Software Engineering

Année:

2014

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2014

39

Book reviews

Bigger, Stephen, Tucker, J. Brian

Journal:

Journal of Beliefs & Values

Année:

2010

Langue:

english

Fichier:

PDF, 77 KB

english, 2010

40

[IEEE 2011 IEEE 27th International Conference on Software Maintenance (ICSM) - Williamsburg, VA, USA (2011.09.25-2011.09.30)] 2011 27th IEEE International Conference on Software Maintenance (ICSM) - Toward a metrics suite for source code lexicons

Biggers, Lauren R., Eddy, Brian P., Kraft, Nicholas A., Etzkorn, Letha H.

Année:

2011

Langue:

english

Fichier:

PDF, 107 KB

english, 2011

41

Perspectives on Gene Therapy for Cystic Fibrosis Airway Disease

Brian Bigger,Dr Charles Coutelle

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 482 KB

english, 2001

42

Xenogenic Transfer of Isolated Murine Mitochondria into Human ρ 0 Cells Can Improve Respiratory Function

Katrangi, Eyad, D'Souza, Gerard, Boddapati, Sarathi V., Kulawiec, Mariola, Singh, Keshav K., Bigger, Brian, Weissig, Volkmar

Journal:

Rejuvenation Research

Année:

2007

Langue:

english

Fichier:

PDF, 256 KB

english, 2007

43

Pre-clinical workup of lentiviral mediated stem cell gene therapy for mucopolysaccharidosis type IIIA

Ellison, Stuart M., Sergijenko, Ana, Langford-Smith, Alex, Langford-Smith, Kia, Wilkinson, Fiona, Wynn, Rob, Bigger, Brian

Journal:

Molecular Genetics and Metabolism

Année:

2015

Langue:

english

Fichier:

PDF, 49 KB

english, 2015

44

An investigation of the middle and late behavioural phenotypes of Mucopolysaccharidosis Type-III

Cross, Elaine M, Grant, Sheena, Jones, Simon, Bigger, Brian W, Wraith, James E, Mahon, Louise V, Lomax, Michelle, Hare, Dougal J

Journal:

Journal of Neurodevelopmental Disorders

Année:

2014

Langue:

english

Fichier:

PDF, 404 KB

english, 2014

45

The role of antibodies in enzyme treatments and therapeutic strategies

Bigger, Brian W., Saif, Muhammad, Linthorst, Gabor E.

Journal:

Best Practice & Research Clinical Endocrinology & Metabolism

Année:

2015

Langue:

english

Fichier:

PDF, 366 KB

english, 2015

46

Development of an adeno-associated viral vector for mucopolysaccharidosis IIIC

O'Leary, Claire, Antunes, Andre, Parker, Helen, Henckaerts, Els, Linden, Michael, Wilkinson, Fiona, Pshezhetsky, Alexey, Bigger, Brian

Journal:

Molecular Genetics and Metabolism

Année:

2015

Langue:

english

Fichier:

PDF, 54 KB

english, 2015

47

Busulfan Conditioning Enhances Engraftment of Hematopoietic Donor-derived Cells in the Brain Compared With Irradiation

Wilkinson, Fiona L, Sergijenko, Ana, Langford-Smith, Kia J, Malinowska, Marcela, Wynn, Rob F, Bigger, Brian W

Journal:

Molecular Therapy

Année:

2013

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2013

48

Enzyme replacement therapy prior to haematopoietic stem cell transplantation in Mucopolysaccharidosis Type I: 10year combined experience of 2 centres

Ghosh, Arunabha, Miller, Weston, Orchard, Paul J., Jones, Simon A., Mercer, Jean, Church, Heather J., Tylee, Karen, Lund, Troy, Bigger, Brian W., Tolar, Jakub, Wynn, Robert F.

Journal:

Molecular Genetics and Metabolism

Année:

2016

Langue:

english

Fichier:

PDF, 516 KB

english, 2016

49

Sterols and Oxysterols in Plasma from Smith-Lemi-Opitz Syndrome Patients

Griffiths, William J., Abdel-Khalik, Jonas, Crick, Peter J., Ogundare, Michael, Shackleton, Cedric H., Tuschl, Karin, Kwok, Mei Kwun, Bigger, Brian W., Morris, Andrew A., Honda, Akira, Xu, Libin, Port

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

2016

Langue:

english

Fichier:

PDF, 758 KB

english, 2016

50

Characterisation of central versus peripheral tumour associated macrophages in glioblastoma multiforme

Youshani, Amir Saam, Yu, Kenny, O'Leary, Claire, Pathmanaban, Omar, Kamaly-Asl, Ian, Bigger, Brian

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 53 KB

english, 2016